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Additional file 1 of Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals

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NIAID Data Ecosystem2026-03-13 收录
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https://figshare.com/articles/dataset/Additional_file_1_of_Impact_of_BMI_and_waist_circumference_on_epigenome-wide_DNA_methylation_and_identification_of_epigenetic_biomarkers_in_blood_an_EWAS_in_multi-ethnic_Asian_individuals/16841289
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Additional file 1: Table S1-S9. Table S1. Summary clinical characteristics of samples. Table S2. Quality control (QC) of DNA methylation data. Table S3. Epigenome-wide association results of obesity-associated CpGs (PFDR<0.05) in Asian samples by sample set, ethnicity and meta-analyses. Table S4. Summary of lookups of previously reported association results in our trans-ethnic meta-analysis. Table S5. Summary of lookups of association results from our trans-ethnic meta-analysis in KORA and LOLIPOP. Table S6. Pathway coefficients in cross-lagged panel model (CLPM) with 116 BMI-associated CpGs for BMI and methylation. Table S7.  Results of forward Mendelian randomization for methylation as the cause. Table S8. Results of backward Mendelian randomization for BMI as the cause. Table S9. Pathway coefficients in cross-lagged panel model (CLPM) with 116 BMI-associated CpGs for metabolomics biomarkers and methylation risk score.
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2021-10-20
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