Voxel-based morphometry (VBM) findings demonstrating grey matter volumes in cerebellum subregions showing a significant correlation with ACE-R, CBI-R and ALSFRS-R (p<0.05).

Cerebellar subregions are grouped based on functional neuroimaging and connectivity studies indicating ‘sensorimotor’ cerebellar regions (marked *) and ‘cognitive’ cerebellar regions (boxed). Within cerebellar lobules, atrophy in the medial (deeper cerebellar regions), lateral (external cerebellar regions) or both (across medial and lateral) regions are noted.