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Single-cell reconstitution reveals persistence of clonal heterogeneity in the murine hematopoietic system

NIAID Data Ecosystem2026-03-13 收录

单细胞造血谱系追踪

肿瘤克隆异质性分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174040 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2022-08-31

癌症治疗反应

肿瘤克隆异质性分析

Triple-negative breast cancer, characterized by aggressive growth and high intratumor heterogeneity, presents a significant clinical challenge. Here, we use a lineage-tracing system, ClonMapper, which

NIAID Data Ecosystem30

Dataset of tugHall simulations of cell evolution for colorectal cancer

结直肠癌进化模拟

肿瘤克隆异质性分析

Dataset contains results of multiply parallel calculations using the tugHall simulator. Output data of simulations are variant allele frequencies for four genes (APC, KRAS, TP53, and PIK3CA) related t

NIAID Data Ecosystem30

Exome sequencing of samples taken at multipl time points to monitor therapy response in AML

AML精准治疗监测

肿瘤克隆异质性分析

As part of our individualized systems medicine program, personalized treatment options are identified and administered to chemorefractory AML patients based on exome sequencing and ex-vivo drug sensit

NIAID Data Ecosystem20

Spatial genomics enables multi-modal study of clonal heterogeneity in tissues

空间多组学

肿瘤克隆异质性分析

The state and behavior of a cell can be influenced by both genetic and environmental factors. In particular, tumor progression is determined by underlying genetic aberrations as well as the makeup of

NIAID Data Ecosystem30

Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer

非小细胞肺癌耐药性

肿瘤克隆异质性分析

To study the interaction between mutated clones using interspecies competition and mathematical models Methods: RNA was extracted from 3-D cultures after 48 hours of growth in spheroids using manufact

NIAID Data Ecosystem20

Single-cell reconstitution reveals persistence of clonal heterogeneity in the murine hematopoietic system

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