Protein kinase A catalytic subunit in complex with PKI5-24 and EN068
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Protein kinase A catalytic subunit in complex with PKI5-24 and EN068 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-azanyl-5-[3-[(2R)-morpholin-2-yl]phenyl]benzenecarbonitrile, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Glinca, S, Mueller, J.M, Ruf, M, Merkl, S. Deposit date: 2021-08-19 Release date: 2022-09-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.427 Å) Cite: Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces. J.Med.Chem., 65, 2022
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2021-08-19
