Ubiquitous environmental and endogenous genotoxic agents cause DNA lesions that can interfere with normal DNA metabolism including DNA replication, eventually resulting in mutations that lead to carci
*recA expression could not be evaluated in the null recA mutant, but was not regulated by umuDAb. ** umuDAb expression could not be evaluated in the null umuDAb mutant, but was regulated by recA.
Ovarian cancer (OC) is the common gynecological malignancy in women. PARP inhibitors (PARPi) have been approved for ovarian cancer treatment, especially for BRCA-deficient patients. However, the prima
Crystal structure of Crb2 tandem tudor domains Descriptor: DNA repair protein rhp9/CRB2, PHOSPHATE ION Authors: Lee, J, Botuyan, M.V, Thompson, J.R, Mer, G. Deposit date: 2005-12-23 Release date: 2007