Metagenomic data (ECOBABe trial)

The ECOBABe Trial was a single-blinded randomised placebo-controlled pilot trial that assessed whether oral administration of maternal vaginal microbes could restore gut microbiome development in infants born by caesarean section (CS). <br>The trial recruited 25 women having an elective CS and randomised their neonates 1:1 to receive a 3 ml solution of maternal vaginal microbes (CS-seeded, n=12) or sterile water (CS-placebo, n=13). A group of vaginally born infants served as a reference control (VB, n=22). <br>Shotgun metagenomics was performed on a total of 116 samples. This included 45 infant stool samples collected at 1 month of age, 46 infant stool samples collected at 3 months of age, and 25 maternal vaginal samples (from CS mothers).<br>This dataset contains:1. Sample metadata2. KneadData read count table3. MetaPhlAn2 relative abundance taxonomy table4. HUMAnN2 gene families table (normalised to CPM)5. HUMAnN2 pathways abundance table (normalised to CPM)6. StrainPhlAn FASTA files (SNP haplotypes)