Functional characteristics of the ASIC1a constructs.
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ASIC1a currents (INa) were elicited at pH 6.0. ΔCCt denotes ASIC1a mutant lacking the cysteines in the C-terminus. BMOE (2mM), Cd2+ and DTT (10 mM) were added in the extracellular medium. ** denotes statistical significance p<0.01 and * p<0.05, unpaired t-test for the mutant compared to ASIC1a wt. denotes p<0.01 for treated versus untreated condition. Current values (μA or % of control) are expressed as mean ± SD IC0.5 and pH0.5 are expressed as best-fit values ± 95% confidence intervals of at least 4 independent experiments Functional characteristics of the ASIC1a constructs.
创建时间:
2015-08-07



