Human NAMPT in complex with inhibitor ZN-4-3
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Human NAMPT in complex with inhibitor ZN-4-3 Descriptor: (3S)-N-[(1-benzothiophen-5-yl)methyl]-1-[6-(4-{2-[(2E)-3-(pyridin-3-yl)prop-2-enamido]ethyl}phenyl)thieno[2,3-d]pyrimidin-4-yl]piperidine-3-carboxamide, CHLORIDE ION, GLYCEROL, ... Authors: Ratia, K, Xiong, R, Shen, Z, Thatcher, G.R. Deposit date: 2022-07-22 Release date: 2023-08-02 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.75 Å) Cite: A structural mechanism for positive allosteric modulation of nicotinamide phosphoribosyltransferase to elevate cellular NAD+ To Be Published
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2022-07-22
