The Eµ-Myc mouse is an extensively used model of MYC-driven malignancy. We performed whole-genome sequencing and exome sequencing to define the transgene architecture, somatic mutations, and structura
Uptake is expressed as % ID/g and presented as an average value from 4 animals ± S.D. “Naive” and “Tumor”, indicate healthy mice and mice challenged with subcutaneous T241 fibrosarcomes, respectively.
Human lymphoid malignancies are often characterized by oncogenic translocations involving the antigen receptor gene loci. CtIP is a DNA end-resection factor that has been widely implicated in alternat
