SNP-rich gene expression hubs, connecting myelin-related and synaptic dysfunction in schizophrenia.

Stable 1: Summary information for all genes with positively correlating genes based on expression data in the Allen Brain Atlas [2, 3]. Pairwise gene expression correlations taken from [4]. Differential methylation values in schizophrenic patients were taken from [1] and summed up for the "correlation neighbors" (i.e. genes having a Pearson correlation of min. 0.8) of each gene.

References

1. Wockner LF, Noble EP, Lawford BR, Young RM, Morris CP, Whitehall VL, Voisey J: Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients. Transl Psychiatry 2014, 4:e339.
2. Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL et al: An anatomically comprehensive atlas of the adult human brain transcriptome. Nature 2012, 489(7416):391-399.
3. Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Ebbert A, Riley ZL, Royall JJ, Aiona K et al: Transcriptional landscape of the prenatal human brain. Nature 2014, 508(7495):199-206.
4. Wu Y, Yao YG, Luo XJ: SZDB: A Database for Schizophrenia Genetic Research. Schizophr Bull 2016.