Crystal structure of wild type HIV-1 protease with novel P1'-ligand GRL-02031
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Crystal structure of wild type HIV-1 protease with novel P1'-ligand GRL-02031 Descriptor: (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, CHLORIDE ION, GLYCEROL, ... Authors: Tie, Y, Wang, Y.F, Weber, I.T. Deposit date: 2009-04-21 Release date: 2009-06-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.29 Å) Cite: Design of HIV-1 protease inhibitors with pyrrolidinones and oxazolidinones as novel P1'-ligands to enhance backbone-binding interactions with protease: synthesis, biological evaluation, and protein-ligand X-ray studies. J.Med.Chem., 52, 2009
创建时间：
2009-04-21
