Rapid and modular workflows for same-day sequencing-based detection of bloodstream infections and antimicrobial resistance determinants

Bloodstream infections (BSI) are a major global health concern, and existing diagnostic methods are too slow to guide targeted antibiotic therapy for critically ill patients, risking poor clinical outcomes. To accelerate microbiological diagnosis, we developed a rapid, and modular metagenomic Next Generation Sequencing-based host DNA depletion workflow named M-15