Suppression of T cell proliferation by rfNSCs expressing IDO.
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(A) The result of mixed leukocyte reaction showed that T cell proliferation was significantly suppressed by both rfNSCs-Cont and rfNSCs-IDO groups. Moreover, the T cell number in the rfNSCs-IDO group was significantly reduced compared to that in the rfNSCs-Cont group. (B) With the treatment of IDO inhibitor, 1-MT (1-methyl-DL-tryptophan) at a 0.5 mM concentration, the T cell number in the rfNSCs-IDO group became similar to that in the rfNSCs-Cont group. (n = 3, *** p
创建时间:
2016-02-23



