Skeletal muscle unloading affects muscle progenitor cells functional activity. Skeletal muscle unloading affects muscle progenitor cells functional activity

In this work we employed classic skeletal muscle unloading rat model to determine how hindlimb suspension (HS) affects functional activity of skeletal muscle progenitor cells (SMPC). We have purified SMPC from m. soleus from control rats and after 1, 3, 7 and 14 days of exposure (HS1, HS3, HS7, HS14). Overall design: Libraries were prepared with TruSeq Stranded mRNA kit, samples were RNA-sequenced on Illumina NextSeq 2000, read length 51 bp. Project was supported by RSF grant №20-75-10080.