Crystal structure of human FPPS in complex with CL01131
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Crystal structure of human FPPS in complex with CL01131 Descriptor: ({[6-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methanediyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, PHOSPHATE ION Authors: Park, J, Leung, C.Y, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2013-07-16 Release date: 2014-06-25 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. J.Med.Chem., 57, 2014
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2013-07-16
