Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of human Fab PGT121, a broadly reactive and potent HIV-1 neutralizing antibody Descriptor: GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PGT121 heavy chain, ... Authors: Julien, J.-P, Diwanji, D.C, Burton, D.R, Wilson, I.A. Deposit date: 2013-03-29 Release date: 2013-05-15 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathog., 9, 2013
创建时间：
2013-03-29
