Cenobamate exhibit prophylactic and therapeutic efficacy against cisplatin-induced peripheral neuropathy in rats: Behavioral and mechanistic insights
收藏DataCite Commons2026-04-15 更新2026-05-04 收录
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https://data.mendeley.com/datasets/ywppb72nt8
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资源简介:
This dataset contains behavioral and immunohistochemical data from the study "Cenobamate exhibits prophylactic and therapeutic efficacy against cisplatin-induced peripheral neuropathy in rats: Behavioral and mechanistic insights."
Behavioral assessmentS in cisplatin-treated rats include:
- *Sensory*: mechanical allodynia (dynamic plantar aesthesiometer), cold allodynia (acetone drop test), thermal hyperalgesia (Hargreaves test)
- Motor: rotarod performance and footprint gait analysis
-Immunohistochemical analyses report H-score quantification of BDNF, cleaved caspase-3, and IL-1β in dorsal root ganglia and sciatic nerve tissues.
Excel files contain raw and processed values for statistical analysis across prophylactic and therapeutic protocols, comparing cenobamate with cisplatin-only and gabapentin-treated control groups.
提供机构:
Mendeley Data
创建时间:
2026-04-15



