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Effect of paraquat and nicotine on gene expression in a Drosophila melanogaster Parkinson's disease model

ChEBI2012-09-05 更新2026-07-21 收录

帕金森病分子机制

果蝇毒理基因组学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35930 数据链接链接失效反馈

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Effect of paraquat and nicotine on gene expression in a Drosophila melanogaster Parkinson's disease model

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创建时间：

2012-09-05

帕金森病分子机制

视黄酸信号通路

a-Synuclein (a-Syn) is a protein implicated in the pathogenesis of Parkinson's disease (PD). It is primarily cytosolic and reversibly interacts with cell membranes. a-Syn also occurs in the nucleus, h

NIAID Data Ecosystem90

Additional file 5: Table S2. of Hexokinases link DJ-1 to the PINK1/parkin pathway

帕金森病分子机制

代谢组学分析

Complete list of biochemicals quantified in DJ-1 knockout mouse brains (TIFF 91 kb) (XLSX 21 kb)

Figshare2017-09-30 更新80

Table_1_Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein.XLSX

帕金森病分子机制

多组学分析

LUHMES cells share many characteristics with human dopaminergic neurons in the substantia nigra, the cells, the demise of which is responsible for the motor symptoms in Parkinson's disease (PD). LUHME

NIAID Data Ecosystem40

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

帕金森病分子机制

Hedgehog信号通路

Previously, we showed that cholinergic interneurons of the dorsal striatum lose cilia in mice harboring the Parkinsonâs disease associated, kinase activating, R1441C LRRK2 mutation (Dhekne et al., 2

DataONE2021-11-22 更新80

Transcriptional interaction network analyses in dorsal nucleus of vagus nerve, locus coeruleus and substantia nigra in Parkinson's disease

帕金森病分子机制

神经细胞转录组学

We analyzed the transcriptomic profile of post-mortem explants from dorsal nucleus of vagus nerve, locus coeruleus and substantia nigra obtained from controls and Braak 4 (BK4) and 5 (BK5) stages of P

NIAID Data Ecosystem60

Effect of paraquat and nicotine on gene expression in a Drosophila melanogaster Parkinson's disease model

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