An Eficient One-Pot Synthesis of Macrocyclic Compounds Possessing Propargylamine Skeletons via Mannich Reaction
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下载链接:
http://www.thieme-connect.com/DOI/DOI?10.1055/s-0031-1289904
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资源简介:
A new efficient method using the Mannich three-component reaction
in one pot to synthesize [1+2+1]-
and [2+4+2]-macrocyclic compounds
possessing a propargylamine backbone was reported. Interestingly,
1,4-diazepane as a multiuse reagent played the part of a substrate
to participate in the Mannich reaction and acted as a base to promote
the Eglinton-Glaser dimerizations in the coordination processes
simultaneously via a one-pot procedure. The target macrocycles were
obtained in good yields.
提供机构:
Georg Thieme Verlag, Stuttgart, New York
创建时间:
2011-12-12



