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An Eficient One-Pot Synthesis of Macrocyclic Compounds Possessing Propargylamine Skeletons via Mannich Reaction

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DataCite Commons2020-09-23 更新2024-07-13 收录
下载链接:
http://www.thieme-connect.com/DOI/DOI?10.1055/s-0031-1289904
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资源简介:
A new efficient method using the Mannich three-component reaction in one pot to synthesize [1+2+1]- and [2+4+2]-macrocyclic compounds possessing a propargylamine backbone was reported. Interestingly, 1,4-diazepane as a multiuse reagent played the part of a substrate to participate in the Mannich reaction and acted as a base to promote the Eglinton-Glaser dimerizations in the coordination processes simultaneously via a one-pot procedure. The target macrocycles were obtained in good yields.
提供机构:
Georg Thieme Verlag, Stuttgart, New York
创建时间:
2011-12-12
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