Type4_Diao_distr_2_1212_100_13_3_Enhancers

NIAID Data Ecosystem2026-03-11 收录

增强子筛选

基因调控功能验证

数据链接：

https://figshare.com/articles/dataset/Type4_Diao_distr_2_1212_100_13_3_Enhancers/8251238 数据链接链接失效反馈

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Enhancer positions from simulated CRISPR regulatory screen. Type 4, high guide counts, high selection strength

创建时间：

2019-06-20

RNA-seq on MCF10A-YAP5SA cells (overexpressed constrictively activated YAP in MCF10A cells) transduced with sgRNAs vectors targeting the TEAD4 binding motif within the identified enhancers

YAP信号通路

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We performed a CRISPR-based functional genetic screen targeting TEAD4 binding motif located within the YAP-bound enhancers. The screen identified seven functional enhancers whose targeting resulted i

NIAID Data Ecosystem90

Type1_Fulco_distr_1212_15_4_5_Enhancers

增强子筛选

基因调控

Enhancer positions from simulated CRISPR regulatory screen. Type 1, medium guide counts, low selection strength

Figshare2019-06-20 更新70

Mapping the regulatory potential of fixed variants in modern humans. Mapping the regulatory potential of fixed variants in modern humans

进化基因组学

基因调控功能验证

The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ between modern and archaic humans, the majority of which are noncoding. However, our understanding of the regulator

NIAID Data Ecosystem50

synthetic construct Raw sequence reads

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大规模并行报告基因分析

The Orthodenticle homeobox (Otx) gene is a conserved homeobox gene, crucial for patterning the anterior neural plate of vertebrate embryos. In the invertebrate chordate Ciona intestinalis, Ci-Otx is a

NIAID Data Ecosystem90

Networking Senescence-Regulating Pathways by Using Arabidopsis Enhancer Trap Lines

叶片衰老调控

增强子筛选

The last phase of leaf development, generally referred to as leaf senescence, is an integral part of plant development that involves massive programmed cell death. Due to a sharp decline of photosynth

PubMed Central50

Type4_Diao_distr_2_1212_100_13_3_Enhancers

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