Summary of clinical characteristics for 121 patients with EM and association of the significance of spirochete number with clinical characteristic.

aAs determined by Mann-Whitney test.
bSystemic symptoms comprised fatigue, headache, myalgia, arthralgia, malaise, rigors, dizziness, nausea and fever.
cSymptoms at site comprised itching, burning and pain.
dHistory of extracutaneous LB and/or EM, previously diagnosed by a physician; data not available for 1 patient (i.e.) n = 120.
eChronic underlying illness; arterial hypertension, hyperlipidemia, osteoporosis, diabetes mellitus, thyroid disease, cardiac rhythm abnormality, psychiatric illness, ischemic heart disease, osteoarthritis or asthma.
fPatients had malignancy and were treated with chemo−/radiotherapy within the last year.