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Bulk RNA-seq of siGFPT2 and NC grouped H1975 cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269440
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In the evolving field of cancer immunotherapy, EGFR-mutated NSCLC presents a significant challenge, demonstrating marked resistance to established treatments. An effective method to counter this resistance remains elusive. Through comprehensive genetic and pharmacological analyses across various models, we have identified glutamine fructose-6-phosphate transaminase 2 (GFPT2) as a key facilitator of immune evasion in EGFR-mutated NSCLC. In this experiment, we analyzed NC and siGFPT2 grouped H1975 cells on Illumina Novaseq 6000 platform to investigate the differential gene expression.
创建时间:
2024-06-10
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