Adjusted mean (SE) changes from baseline in FEV₁ AUC_0–4h overall and in patients (aged ≤11 years and ≥12 years) treated with tiotropium (2.5 or 5 µg) or placebo after 12 weeks^*.

*Analysis of the full analysis set study group based on mixed-effect model with repeated measures model using unstructured covariance matrix. AUC0–4h, area under the curve from 0 to 4 hours; CI, confidence interval; FEV1, forced expiratory volume in 1 second; SE, standard error. Adjusted mean (SE) changes from baseline in FEV1 AUC0–4h overall and in patients (aged ≤11 years and ≥12 years) treated with tiotropium (2.5 or 5 µg) or placebo after 12 weeks*.