Text S1 - Characterisation of Clostridium difficile Hospital Ward–Based Transmission Using Extensive Epidemiological Data and Molecular Typing

Additional methods and results. Table A: Interventions in place at the start of the study (1 September 2007), and changes during the study (through 31 March 2010). Table B: Network characteristics. Figure A: C. difficile tests and EIA-positive tests over the study period. Using 28-d de-duplication (i.e., not counting repeat tests/positives within 28 d of an index test/positive as a new event). Figure B: Distribution of infectious and incubation periods for transmissions within 69 sequence types and 705 test CDI cases. All potential transmission links where the direction of transmission is known (ward contact after potential donor CDI and before recipient CDI) are plotted assuming maximum allowable infection and incubation periods of 26 wk and no ward contamination persisting after donor discharge (see Results for distributions from the most plausible links). Times are plotted rounded up to the nearest week, e.g., intervals of 0–6 d are plotted as 1 wk. (DOC)