RNA-sequencing of human embryonic and fetal urinary bladder and genital tissues

The general aim is to provide knowledge of transcriptomic profiles of the developing urinary bladder in order to shed light on gene expression important in the mechanisms behind the developmental defects of bladder exstrophy. Human bladder tissues and gential tissues, as control samples, were surgically removed from terminated fetuses after informed consent and ethical approval. Gene expression data were extracted and analysed after high throughput sequencing of paired-end mRNA libraries (Illumina).