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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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创建时间：
2023-08-22
相关数据集
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia
We report here an efficient, reproducible model of T-cell leukemia in which lentiviral transduction of normal human cord blood yields aggressive leukemia that appears indistinguishable from natural di
NIAID Data Ecosystem30
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]
Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe
NIAID Data Ecosystem30
Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice
The MLL-ELL fusion gene results from the translocation t(11;19)(q23;p13.1) that is associated with de novo and therapy-related acute myeloid leukemia. To study its transforming properties, we retrovir
PubMed Central2000-09-19 更新20
Table S2 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
Table S2 shows differentially expressed genes by RNA-seq
Figshare2019-09-01 更新30
Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia [ATAC-seq]
MGA (Max-gene associated) is a dual-specificity transcription factor that negatively regulates MYC-target genes to inhibit proliferation and promote differentiation. Loss-of-function mutations in MGA
NIAID Data Ecosystem20
