Structure of the B-Raf kinase domain bound to SB-590885
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Structure of the B-Raf kinase domain bound to SB-590885 Descriptor: (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, B-Raf proto-oncogene serine/threonine-protein kinase Authors: Lougheed, J.C, Lee, J, Chau, D.C, Stout, T.J. Deposit date: 2005-12-08 Release date: 2006-12-12 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885. Cancer Res., 66, 2006
创建时间：
2005-12-08
