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Supplementary Data S12 - PRO-seq gene body analysis

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DataCite Commons2025-12-16 更新2026-02-09 收录
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Supplementary Data S12 of the manuscript "<b>Hypoxia leads to reduced mito-nuclear gene expression and to increased mtDNA transcriptional pausing in human cells</b>" by Shtolz et al.Result of DESeq2 analysis on PRO-seq data analyzed using PEPPR."result" output. Main columns:<b>Name:</b> gene symbol<b>baseMean</b>: Mean normalized expression across all samples<b>log2FoldChange</b>: log<sub>2</sub> fold-change between treatment (hypoxia) and control (normoxia).<b>lfcSE</b>: Standard error of the log<sub>2</sub><sub> </sub>fold-change<b>stat</b>: Negative binomial test statistic.<b>p-value</b><b>padj:</b> Benjamin-Hodgkin-adjusted p-value<b>dataset</b>: Name of the dataset<b>cell line</b><b>Complex</b>: Complex association of gene (either complex I, II, III, IV and V of OXPHOS or the mito-ribosome)<b>Genome</b>: Genome of the gene (NUC for nucleus or MT for mitochondrial DNA).<b>ensembl.gene</b>: Ensemble gene ID.Data used to generate Supplementary Fig. S11.
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2025-12-16
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