List of known invitro and invivo amino acid substitutions resistant to NS5B polymerase inhibitors used in this study (NS5B residues 244–496).
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*[6], [9], [11], [15]–[18], [54], [55].**L320F when in combination with L159F confers low level resistance to MCB [9], L320I or V321I when in combination with C223H confers low level resistance to GS-938 [54].
创建时间:
2015-12-02



