Gene Expression in Cx3cr1-GFP+ Cells in PS2APP Alzheimer's Disease mice
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=fb3be8834f5a3fb868f8c868ab43f83e
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This project defines the microglial gene expression profile in a transgenic mouse model of Alzheimer's, compared to non-transgenic age-matched controls, at a time when amyloid pathology and microgliosis are rampant. Microglia were sorted live from one hemisphere of cerebral cortex, using GFP expressed from Cx3cr1 locus (mice have one intact copy of Cx3cr1). RNA was isolated from sorted microglia using RNeasy mini. Two groups, PS2APP and non-transgenic, with 9 mice/group, aged 14-15 months.The "SAMPLE_ID" sample characteristic is a sample identifier internal to Genentech.The ID of this project in Genentech's ExpressionPlot database is PRJ0006715
提供机构：
Genentech, Inc.
创建时间：
2022-02-20
