Tracking DNA synthesis during break-induced replication reveals key mechanistic insights and stalling at roadblocks
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
Interstitial telomere sequences (ITSs) as one of the CFSs has been demonstrated to causing genomic instability during normal DNA replication but how it affects DNA synthesis during Break-induced replication (BIR) is still unknown. Using our yeast system, we inserted an ITS sequence on the template of BIR, and observed a pre-matured BIR product, which didn't pass through the ITS position.
创建时间：
2020-10-24
