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Fertile offspring derived from mouse spermatogonial stem cells cryopreserved for more than 14 years

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NIAID Data Ecosystem2026-03-07 收录
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To evaluate the possible deleterious affects prolonged cryopreservation and assisted reproductive technologies may have on the DNA of F0 progeny, we used array-based comparative genomic hybridization (CGH) for analysis of genomic DNA. ICSI-derived progeny were generated from ♂ (ZFLacZ sperm) x ♀ (DBA x C57BL/6 oocyte), where the ZFLazZ transgenic mice were originally generated from an SJL x C57BL/6 background.

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2013-05-07
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