Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE267749
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To understand the molecular mechanisms underlying developmental abnormalities in Dyrk2-/- mice, we performed comprehensive whole-genome RNA sequencing of the MEFs from wild-type and Dyrk2-/- embryos We performed gene expression profiling analysis of RNA-seq data for wild-type and Dyrk2-/- MEFs in the presence of 100 nM SAG for 24 h as well as MEFs treated with siDyrk2 or siNegative (siNeg) in the presence of 100 nM SAG for 24 h
创建时间：
2024-07-26
