We report the application of single-molecule-based sequencing technology for high-throughput profiling of naive CD4 T cells. By sequencing this population in young and older donors, we describe the h
Alternative splicing (AS), as a crutical promoter of proteomic diversity, constitutes a core source of cellular heterogeneity together with gene expression levels. AS is closely linked to various phys
Heterogeneity of endothelial cells that form the innermost layer of all vessels is critical for vascular sprouting and angiogenesis. After new vessels form, endothelial cell heterogeneity is believed
Hepatocytes are considered as a heterogenous cell population in the liver. We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of hepatocytes in livers under different feeding cond
