Genetic Status of Unaffected Individuals II∶3 & II∶9 for the Seventeen Shared and Ambiguous Regions.

The letter “X” specifies the region is also shared by the unaffected individual, the letter “P” indicates the region is partially shared and the letter “A” designates the region is ambiguous. The maximum physical size is shown for each region. The shared regions of interest are classified into three categories based on the genomic content of the two unaffected individuals (II∶3 and II∶9). The RI-1 category contains regions that are the most likely to contain the ALS-A gene while the RI-3 category includes regions that are the least likely to hold the gene.