Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor
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Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor Descriptor: N-{3-[(5R)-1-cyclopentyl-4-hydroxy-5-methyl-5-(3-methylbutyl)-2-oxo-1,2,5,6-tetrahydropyridin-3-yl]-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase Authors: Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. Deposit date: 2009-04-04 Release date: 2009-12-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.15 Å) Cite: 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2009-04-04
