Natural killer (NK) cell function is regulated by a balance between activating and inhibitory receptors, but the details of this receptor interplay are not extensively understood. We developed a flow

NIAID Data Ecosystem60

MOESM10 of Silencing of one copy of the translation initiation factor eIFiso4G in Japanese plum (Prunus salicina) impacts susceptibility to Plum pox virus (PPV) and small RNA production

植物病毒抗性

基因沉默技术

Additional file 10: Table S4. List of primers used for the production of RNAi constructs, the verification of transgenic lines and the estimation of relative expression analysis. 1 In italics, sequenc

Figshare2019-10-22 更新30

From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

前列腺癌信号通路

受体调控

Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the growth of prostate cancer LNCaP cells can also be increased by the stable

PubMed Central1999-05-11 更新60

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A 2A Receptor

受体调控

分子药理学

The sodium ion site is an allosteric site conserved among many G protein-coupled receptors (GPCRs). Amiloride 1 and 5-(N,N-hexamethylene)amiloride 2 (HMA) supposedly bind in this sodium ion site and

NIAID Data Ecosystem40

shRNA suppressing mus musculus Freud-1 gene. shRNA mus Freud-1

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