five

Genome-wide Discovery of Novel M1T1 Group A Streptococcal Determinants Important for Fitness and Virulence During Soft-Tissue Infection. Streptococcus pyogenes strain:5448

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA391181
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A near saturation mariner mutant library produced in the Streptococcus pyogenes strain 5448 was screened by Tn-seq in an in vivo mouse model of subepithelial tissue infection. Ratios of mutant abundance were determined at different times points (12, 24 and 48 h post-infection). Two yet uncharacterized genes, scfA and scfB, encoding putative membrane-associated proteins were further characterized, and RNA-seq data used to look at scfAB transcription.
创建时间:
2017-06-20
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