Pyrazolate-Based Porphyrinic Metal–Organic Framework with Extraordinary Base-Resistance

Guided
by a top-down topological analysis, a metal–organic
framework (MOF) constructed by pyrazolate-based porphyrinic ligand,
namely, PCN-601, has been rationally designed and synthesized, and
it exhibits excellent stability in alkali solutions. It is, to the
best of our knowledge, the first identified MOF that can retain its
crystallinity and porosity in saturated sodium hydroxide solution
(∼20 mol/L) at room temperature and 100 °C. This almost
pushes base-resistance of porphyrinic MOFs (even if MOFs) to the limit
in aqueous media and greatly extends the range of their potential
applications. In this work, we also tried to interpret the stability
of PCN-601 from both thermodynamic and kinetic perspectives.