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Multiconformer model of K197C PTP1B tethered to compound 2 at 100 K

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Multiconformer model of K197C PTP1B tethered to compound 2 at 100 K Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-(2',4'-difluoro-4-hydroxy[1,1'-biphenyl]-3-yl)-2-sulfanylacetamide, Tyrosine-protein phosphatase non-receptor type 1 Authors: Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. Deposit date: 2017-10-10 Release date: 2018-06-20 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018

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2017-10-10
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