Crystal structure of BTK kinase domain complexed with 4-Methanesulfonyl-N-(3-{8-[4-(morpholine-4-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4ot6
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of BTK kinase domain complexed with 4-Methanesulfonyl-N-(3-{8-[4-(morpholine-4-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide Descriptor: 4-(methylsulfonyl)-N-[3-(8-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}imidazo[1,2-a]pyrazin-6-yl)phenyl]benzamide, Tyrosine-protein kinase BTK Authors: Kuglstatter, A, Wong, A. Deposit date: 2014-02-13 Release date: 2014-05-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structure-Based Drug Design of RN486, a Potent and Selective Bruton's Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis. J.Med.Chem., 58, 2015
创建时间：
2014-02-13
