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Source files for 'Signaling Specificity Defined by Unique Transitions in G Protein Conformations'

NIAID Data Ecosystem2026-05-10 收录

G蛋白信号传导

构象动力学

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https://figshare.com/articles/dataset/_Supplemental/30418240 数据链接链接失效反馈

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Source files for 'Signaling Specificity Defined by Unique Transitions in G Protein Conformations'

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创建时间：

2025-10-22

胰岛素结构

构象动力学

We have investigated the structure and conformational dynamics of insulin dimer using a Markov state model (MSM) built from extensive unbiased atomistic molecular dynamics simulations and performed in

NIAID Data Ecosystem90

Computational Simulation of the Activation Cycle of Gα Subunit in the G Protein Cycle Using an Elastic Network Model

蛋白质动力学模拟

G蛋白信号传导

Agonist-activated G protein-coupled receptors (GPCRs) interact with GDP-bound G protein heterotrimers (Gαβγ) promoting GDP/GTP exchange, which results in dissociation of Gα from the receptor and Gβγ.

Figshare2016-08-03 更新60

Intrinsically disordered regions couple the ligand binding and kinase activation of Trk neurotrophin receptors

神经元信号传导

构象动力学

Blot figures, graph data, NMR pulse sequence, diffusion data, confocal microscopy images and flow cytometry data.

NIAID Data Ecosystem50

HETEROTRIMERIC COMPLEX OF PHOSDUCIN/TRANSDUCIN BETA-GAMMA

结构生物学

G蛋白信号传导

HETEROTRIMERIC COMPLEX OF PHOSDUCIN/TRANSDUCIN BETA-GAMMA Descriptor: FARNESYL, PHOSDUCIN, TRANSDUCIN (BETA SUBUNIT), ... Authors: Loew, A, Ho, Y.-K, Blundell, T.L, Bax, B. Deposit date: 1997-12-05 Re

Protein Data Bank Japan2024-10-16 更新60

The Distinct Conformational Dynamics of K-Ras and H-Ras A59G

构象动力学

Ras蛋白突变体功能

Ras proteins regulate signaling cascades crucial for cell proliferation and differentiation by switching between GTP- and GDP-bound conformations. Distinct Ras isoforms have unique physiological funct

NIAID Data Ecosystem50

Source files for 'Signaling Specificity Defined by Unique Transitions in G Protein Conformations'

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