Haplotype Transmission Disequilibrium Test (TDT) of association with severe malaria in Gambian, Kenyan and Malawian child-parental trios.

The table shows the common haplotypes (frequency higher than 5%) within each LD block identified in the gene, their frequency and the results of family-based test of association with severe malaria in the three populations of affected child-parental trios. Freq: frequency of the haplotype in trio parents. These are not unbiased estimates of the population frequencies. OR: Odds Ratio comparing the risk of the untransmitted versus the transmitted haplotype. All other abbreviations as in Table 2.