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Analysis of the differential expression of genes in Otub2- knockout mice

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NIAID Data Ecosystem2026-03-14 收录
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Oral and esophageal squamous cell carcinomas (SCCs) are associated with high mortality, yet molecular mechanisms underlying these malignancies are largely unknown. We demonstrate that epigenetic silencing of otubain 2 (OTUB2), a previously recognized oncogene, drives SSCs initiation and drug resistance. Analyze the differential expression of genes in Otub2- knockout mice transcriptionally.

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2022-09-19
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