EGFR wildtype in complex with BI-8128

EGFR wildtype in complex with BI-8128 Descriptor: (6M)-1-{2-[4-(2-methoxyethyl)piperazin-1-yl]-1-methyl-4-[(1S,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]-1H-imidazo[4,5-c]pyridin-6-yl}-6-(4-methoxypyridin-3-yl)-4-methyl-1H-pyrazolo[4,3-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor Authors: Heppner, D.E, Damghani, T, Lin, K.S. Deposit date: 2024-09-12 Release date: 2026-01-28 Last modified: 2026-02-25 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structural Studies of Fourth-Generation EGFR Inhibitors Reveal Insights into Selective T790M and C797S Targeting. Acs Med.Chem.Lett., 2026