Effect of GPR31-signaling on gene expression in LysoDCs during Listeria monocytogenes infection.

GPR31 signaling induced dendrite protrusion of lysozyme-expressing dendritic cells (LysoDCs) into basolateral pockets of M cells. To investigate the effect of GPR31 signaling on LysoDC function during infection, we analyzed the gene expression profile of LysoDCs from WT and Gpr31b-deficient mice at 2 days after L. monocytogenes infection. RNA-seq profiling of LysoDCs prepared from Peyer's patches of WT mice and Gpr31b-deficient mice at 2 days after oral infection of L. monocytogenes. The dataset consists of 4 groups: WT/uninfected, KO/uninfected, WT/infected, and KO/infected (n=3 in each group) .