Control of Oxygen Atom Chirality and Chelate Ring Conformation by Protected/Free Sugar Hydroxyl Groups in Glucose-Pendant Dipicolylamine−Copper(II) Complexes

A pair of copper(II) complexes 1 and 2 exhibit an enantiomeric
chiral center at the oxygen atom that coordinates to the metal
center. The configurations of the oxygen atom chirality and the
chelate ring conformation are simply controlled by protected/free
hydroxyl groups of the sugar moiety, yielding mirror image CD
spectra. In this system, repulsive and attractive forces are used
to regulate chirality on the copper-coordinated oxygen atom both
in the solid state and in solution.