Actication of alpha7 nicotinic receptor regulates herpes simplex virus infection in the central nervous system

mRNA isolated from a mouse microglia cell line, BV2 cells, treated with or without α7 nicotinic receptor agonist, choline, before HSV-1 infection. mRNA expression was examined with the NanoString© platform (www.nanostring.com) utilizing the Mouse Neuropatholgy codeset (NS_Mm_neuropath_V1.0) that measures 760 endogenous and 10 housekeeping (HK) RNAs. RNA from mouse microglia cell line, BV2 cells, treated with (1) mock, (2) α7 receptor agonist, choline, (3) Herpes simplex virus type 1 (HSV-1), and (4) HSV-1 + choline.