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Analysis of mRNA expression in CHAPIR overexpressed heart

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP272681
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资源简介:
To elucidate the molecular mechanism by which cardiac-hypertrophy-associated piRNA (CHAPIR) regulates gene expression, RNA-seq was performed on control or CHAPIR-overexpressing mice heart. Based on RNA-seq data, 720 differentially expressed genes were shown in CHAPIR-overexpressing heart relative to NC control, including 519 upregulated and 201 downregulated genes. Overall design: Total RNAs were extracted from CHAPIR mimic or mimic-negative control (NC) overexpressed heart. Then, high throughput RNA sequencing was performed to identify differences in the gene expression profile.
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2020-10-24
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