Transcriptomic study of NR8383 cells following exposure to multi-walled carbon nanotubes (NM401)

To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 0.17 µg/mL of multi-walled carbon nanotubes (NM401) (100 % cell viability). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 686098 Changes in gene expression in NR8383 cells incubated without (control) or with (0.17 µg/mL) of multi-walled carbon nanotubes (NM401) for 4 h were measured. For each condition, four biological replicates were performed : C1; C2; C3; C4 as controls, T1; T2; T3, T4 as exposed cells.